Pre Conference Focus Day
Tuesday, February 13, 2024
9:00 am Chair’s Opening Remarks
Characterizing the Target Protein for Regulatory Approval & Ease of Formulation
9:15 am Fireside Chat: Assessing Best Practices to Characterize the Target Protein with Sufficiently Specific Assays
Synopsis
- Benchmarking industry practices for characterizing target proteins
- Uncovering the level of specificity of assays and the analytical tools used
- Understanding how implementing analytics early in the process can predict insufficient quality or aberrant proteins
10:00 am Developing Analytics for Safety Packages for Regulatory Submission From Lab to Commercial Scale
Synopsis
- Understanding what aspects of the ingredient and final formulation determine the safety for regulatory submission
- Ensuring the validity of analytical frameworks from lab to commercial scale
- Determining the number of replicates needed to reduce turnaround times
10:30 am Morning Networking Break
Considering Methods to Increase the Robustness & Efficiency of Analytics at Different Scales
11:30 am Integrating Online Analytics to Characterize Process Efficiency at Commercial Scale
Synopsis
- Identifying critical analytics to indicate process efficiency such as temperature, dissolved oxygen, pH, biomass, turbidity, and viscosity
- Exploring the viability of end-to-end online analytics
- Ensuring the sensitivity of process analytics
12:00 pm Roundtable Discussion: Ensuring the Scalability of Analytical Frameworks to Streamline Tech Transfer
Synopsis
- Promoting scalability of analytics through instrument selection
- Highlighting critical bottlenecks in the scalability of measurements
- Utilizing automation to drive efficiency and reduce error
12:30 pm Characterizing Strains’ Responses to Variable Process Parameters to Aid Strain Engineering at R&D Scale
Synopsis
Discussing high throughput techniques to characterize strains’ tolerance and target protein expression to different environmental conditions
Assessing the application of lab-scale data at commercial scale given that the parameters change
Exploring how effective analytics can reduce COGS
1:00 pm Networking Lunch
Utilizing Next-Generation Analytical Techniques & Processing Methods From R&D to Commercial Scale
2:00 pm Implementing Effective Data Storage & Processing Methods to Streamline Data Analysis
Synopsis
- Reviewing principles to ensure effective organization and formatting of data to facilitate further analysis
- Maximizing the standardization and automation of data to develop a consistent in-house framework to save time
- Transitioning from in-house process modelling to more advanced models
2:30 pm Fireside Chat: Comparing Industry Approaches to Analytical Development to Accelerate Commercialization
Synopsis
Collaborating on current approaches and future plans to streamline analytical development to complement R&D
Sharing current industry pain points and critical improvement areas
Overcoming the vendor shortage to meet the market potential of alternative proteins